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What is BONJESTA®?

When diet and lifestyle changes aren’t enough to control your morning sickness, there’s Bonjesta®.

Bonjesta® is designed to be a fast-acting, long-lasting prescription medication that is FDA-approved for the treatment of morning sickness when diet and lifestyle changes don’t work.

Bonjesta®’s multilayer, extended-release tablets are designed to provide rapid and continuous relief of morning sickness symptoms throughout the day and night.

Bonjesta® contains a combination of the ingredients doxylamine succinate and pyridoxine hydrochloride that have a 60+ year record of safety for mother and baby.

Bonjesta® has not been studied in women with hyperemesis gravidarum. It is not known if Bonjesta® is safe and effective in children under 18 years of age.

bonjesta 2pills
Tablets are pink with the image of a pregnant woman on one side and a “D” on the other. Tablets shown not actual size.

Proven results

Studies in pregnant women have shown that the combination of ingredients in Bonjesta® effectively manages morning sickness when diet and lifestyle changes fail to adequately control symptoms.*

  • Based on the Pregnancy-Unique Quantification of Emesis (PUQE) Score, which evaluates the overall severity of morning sickness: hours of nausea, instances of vomiting and retching over a 24-hour period.
Dr. Masterson
Dr. Masterson is a paid spokesperson for Duchesnay USA.

What is morning sickness?

Morning sickness is a misnomer

Morning sickness is also known as “nausea and vomiting of pregnancy” and its symptoms may last well beyond the morning.

The symptoms of morning sickness can range from mild to severe nausea, gagging, retching and vomiting. You can use the PUQE Score to help you and your healthcare provider assess your morning sickness symptoms. This will help you get your symptoms under control so you can get back to being you.

Take the PUQE test

When changing your diet and lifestyle does not relieve your symptoms, it may be time to ask your healthcare provider about Bonjesta®.

How do I take Bonjesta®?

How safe is Bonjesta®?

Scientific studies show that the combination of ingredients in Bonjesta® does not increase the risk of birth defects, even when taken in the first trimester. Also, the American College of Obstetricians and Gynecologists (ACOG) actually recommends the combination of ingredients found in Bonjesta® as the first treatment to try if diet and lifestyle changes don’t work.

In fact, the combination of ingredients in Bonjesta® is one of the most studied drug combinations in pregnancy and:

  • Has a 60+ year record of safety for mother and baby
  • Has been used by over 35 million women worldwide to treat morning sickness

Note: Safety and efficacy studies are based on trials conducted on the combination of ingredients in Bonjesta®, not on Bonjesta® itself.

Bonjesta® was specifically developed for pregnant women and its combination of ingredients has been proven safe for you and your baby.

What are Bonjesta®’s side effects and safety considerations?

The most common side effect of Bonjesta® is drowsiness.

Do not drive, operate heavy machinery or engage in other activities that need your full attention unless your healthcare provider says that you may do so.

Do not drink alcohol or take other central nervous system depressants, such as cough and cold medicines, certain pain medicines and medicines that help you sleep, while taking Bonjesta®. Severe drowsiness can happen or become worse, causing falls or accidents.

These are not all of the possible side effects of Bonjesta®. Please see full Patient Information. You are encouraged to report side effects to the FDA at 1-800-FDA-1088.

Call your healthcare provider for medical advice about side effects.

What are the potential concerns about over-the-counter (OTC) products?

You may be tempted to try products available at your local pharmacy, but keep in mind that not all medications are safe to take during pregnancy.

OTC products that are often used to treat morning sickness:

  • Have not been studied, proven safe and effective or approved by the FDA for use during pregnancy
  • Are not formulated, indicated or approved by the FDA for the treatment of morning sickness
  • Do not always contain the correct active ingredient
  • Do not contain the correct dosage, so you’ll have to cut the pills yourself
  • Are not formulated to provide both immediate and long-lasting relief
  • May contain ingredients that are unsafe for your baby

Indication and important safety information

INDICATION

Bonjesta® is a prescription medicine used to treat nausea and vomiting of pregnancy in women who have not improved with change in diet or other non-medicine treatments.

LIMITATIONS OF USE

It is not known if Bonjesta® is safe and effective in women with severe nausea and vomiting of pregnancy, a condition called hyperemesis gravidarum. Women with this condition may need to be hospitalized.

IMPORTANT SAFETY INFORMATION

Bonjesta® is intended for use in pregnant women. It is not known if Bonjesta® is safe and effective in children under 18 years of age.

Do not take Bonjesta® if you:

  • are allergic to doxylamine succinate, other ethanolamine derivative antihistamines, pyridoxine hydrochloride or any of the ingredients in Bonjesta®. Please refer to the Patient Information leaflet for the complete list of ingredients;
  • take monoamine oxidase inhibitors (MAOIs). Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including Marplan, Nardil, Emsam, Eldepryl, Zelapar, and Parnate.

Before taking Bonjesta®, tell your healthcare provider about all of your medical conditions, including if you: (1) have asthma; (2) have eye problems called increased intraocular pressure or narrow angle glaucoma; (3) have a stomach problem called stenosing peptic ulcer or pyloroduodenal obstruction; (4) have a bladder problem called urinary bladder-neck obstruction; (5) are breastfeeding or plan to breastfeed. Bonjesta® can pass into your breast milk and may harm your baby. You should not breastfeed while using Bonjesta®.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should you take Bonjesta®?

  • Talk to your healthcare provider about how much Bonjesta® to take and when to take it.
  • Take Bonjesta® everyday as prescribed by your healthcare provider. Do not stop taking Bonjesta® without talking to your healthcare provider first.
  • Do not take more than 2 tablets (1 in the morning and 1 at bedtime) each day.
  • Take Bonjesta® on an empty stomach with a glass of water.
  • Take Bonjesta® tablets whole.
  • If you take too much Bonjesta® (overdose), you may have the following symptoms: restlessness, dry mouth, the pupils of your eyes become larger (dilated), sleepiness, dizziness, confusion, fast heart rate, seizures, muscle pain or weakness, urination changes and build-up of fluid in the body. If you have these symptoms and they are severe, they may lead to death. If you take too much Bonjesta®, call your poison control center at 1-800-222-1222.

What are the possible side effects of Bonjesta®?

  • The most common side effect of Bonjesta® is drowsiness.
  • Do not drive, operate heavy machinery, or do other activities that need your full attention unless your healthcare provider says that you may do so. Do not drink alcohol, or take other CNS depressants such as cough and cold medicines, certain pain medicines, and medicines that help you sleep while you take Bonjesta®. Severe drowsiness can happen or become worse causing falls or accidents.
  • Bonjesta® may cause an incorrect positive result for urine drug screening tests for methadone, opiates and PCP.

These are not all the possible side effects of Bonjesta®. Call your doctor for medical advice about side effects.

Keep Bonjesta® and all medicines out of the reach of children. Carefully read the storage instruction as detailed in the Bonjesta Patient Information leaflet.

Duchesnay USA encourages you to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088